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KMID : 1197720120050010009
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대한파킨슨병 및 이상운동질환 학회지
2012 Volume.5 No. 1 p.9 ~ p.13
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Botulinum Toxin Clinic-Based Epidemiologic Survey of Adults with Primary Dystonia in East China
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Wang Li
Hu Xingyue
Liu Chungfeng
Wu Yiwen
Wang Changqing
Wang Zhiquang
Chen Jun
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Abstract
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Background and Purpose: Primary focal or segmental dystonia is a rare clinical condition. The clinical features of dystonia have not been evaluated in China. We performed a study to investigate the epidemiology of primary dystonia and its clinical variants in an adult population.
Methods: A Botulinum Toxin Clinic-based study was conducted in the period 18 May through 8 October 2010 in East China. We identified 523 dystonia patients from the Movement disorders and Botulinum Toxin clinic Cases.
Results: The most common focal dystonia were blepharospasm (59%), cervical dystonia (35%), limb dystonia (3%), oromandibular dystonia (2%) and laryngeal dystonia (1%). Males with primary dystonia were noted to have earlier age of onset. A female predominance was noted for most of the primary dystonias with a male to female ratio (M : F) ranging from 1 : 1.48 to 1 : 3.
Conclusions: The epidemiological features of dystonia in East China we collected were similar to the report in Japan which contrasts partly with that reported in Europe.
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KEYWORD
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Epidemiology, China, Primary dystonia
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